
Feature film — 2010
Splice (2010)
Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.
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A high-signal pick with 2,546 votes.
Copperheart Entertainment / Gaumont / Senator Film / Dark Castle Entertainment
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Director: Vincenzo Natali
On screen
Cast & crew

Adrien Brody
Clive Nicoli

Sarah Polley
Elsa Kast

Delphine Chanéac
Dren

Brandon McGibbon
Gavin Nicoli

Simona Măicănescu
Joan Chorot

David Hewlett
William Barlow

Abigail Chu
Child Dren
Doug Hicton
Lab tech (uncredited)
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